Aldosterone
Aldosterone is a hormone produced by the adrenal cortex. It regulates the body's water and electrolyte balance, helps maintain normal sodium and potassium levels, and plays an important role in blood pressure regulation.
Measurement of aldosterone is used to diagnose adrenal gland disorders, identify the causes of hypertension, and assess the renin–angiotensin–aldosterone system. The test is often performed together with plasma renin measurement.
Indications
The test is recommended in the following situations:
- persistent or difficult-to-control hypertension;
- suspected primary or secondary hyperaldosteronism;
- low blood potassium levels (hypokalemia);
- muscle weakness, muscle cramps, or increased fatigue;
- detection of adrenal gland masses;
- evaluation of patients with suspected adrenal dysfunction;
- monitoring the effectiveness of treatment for disorders associated with abnormal aldosterone secretion.
Procedure
The test requires a venous blood sample.
Aldosterone levels are influenced by body position, time of sample collection, salt intake, and certain medications. Your healthcare provider may recommend specific conditions for blood collection before the test.
Method
Chemiluminescent Immunoassay (CLIA).
Sources:
https://my.clevelandclinic.org/health/articles/24158-aldosterone
https://www.ncbi.nlm.nih.gov/books/NBK470339/
https://medlineplus.gov/lab-tests/aldosterone-test/
IMPORTANT!
It is crucial to remember that the information provided in this section is not intended for self-diagnosis or self-treatment. If you experience any symptoms or a flare-up of a condition, it is essential to consult a healthcare professional for proper diagnostic tests and treatment. Only a qualified specialist can make an accurate diagnosis and determine the appropriate course of treatment. To obtain the most accurate and consistent assessment of test results, it is recommended to have them performed at the same laboratory. Different laboratories may use different methods and units of measurement for similar tests, which can lead to variations in results.
Preparation:
- Blood collection is recommended in the morning unless otherwise instructed by your healthcare provider.
- Do not eat for 8–12 hours before the test; drinking plain water is allowed.
- Avoid intense physical activity and emotional stress for 24 hours before the test.
- Do not smoke for at least 1 hour before blood collection.
- Inform your healthcare provider about all medications you are taking, especially diuretics, antihypertensive drugs, hormonal medications, and potassium supplements, as they may affect the test results. Medications should only be discontinued if recommended by your healthcare provider.
- Follow your healthcare provider's recommendations regarding salt intake before the test, as it may influence aldosterone levels.