Prostate-specific antigen free, fPSA
Free Prostate-Specific Antigen (fPSA) is a laboratory blood test that measures the concentration of the free form of PSA, which is not bound to blood proteins. In combination with total PSA testing, fPSA measurement helps to clarify the risk of pathological changes in the prostate, including benign prostatic hyperplasia and cancer. The test serves as an additional tool for evaluating prostate health and planning further monitoring.
Indications
- Elevated total PSA levels (especially 4–10 ng/mL)
- Need to assess prostate cancer risk
- Monitoring after prostate treatment or intervention
- Suspicion of benign prostatic hyperplasia or other prostate changes
Procedure
- Venous blood is drawn from the elbow vein
- The sample is placed in a tube with an anticoagulant
- The material is sent to the laboratory for free PSA analysis
- Results are available within minutes or hours, depending on the laboratory
Sources:
https://www.healthline.com/health/prostate-cancer-free-psa
https://www.webmd.com/prostate-cancer/low-free-psa-level
https://www.cancer.gov/types/prostate/psa-fact-sheet
https://www.webmd.com/prostate-cancer/psa
https://www.mayoclinic.org/tests-procedures/psa-test/about/pac-20384731
https://www.medicalnewstoday.com/articles/322001
https://www.health.harvard.edu/blog/what-is-the-difference-between-psa-and-free-psa-20091001114
IMPORTANT!
It is crucial to remember that the information provided in this section is not intended for self-diagnosis or treatment. If you experience any pain or exacerbation of a condition, it is necessary to consult a doctor for diagnostic testing. Only a qualified healthcare professional can make an accurate diagnosis and determine the appropriate treatment. To obtain the most accurate and consistent assessment of test results, it is recommended to have them performed at the same laboratory. This is because different laboratories may use varying methods and units of measurement for similar tests.
Preparation:
- Special preparation is usually not required
- It is recommended to fast for 8–12 hours before the test
- Inform your doctor or laboratory staff if you are taking anticoagulants
- Avoid intense physical activity and sexual intercourse 24 hours before the test