Fetal sex determination

Fetal Sex Determination is a non-invasive genetic test that determines the sex of the unborn baby using a blood sample from the pregnant woman. The test is based on the detection of cell-free fetal DNA (cfDNA) circulating in the mother's bloodstream. The presence of Y chromosome-specific DNA sequences indicates a male fetus, while their absence suggests a female fetus.

Indications

• parents wish to learn the baby's sex early in pregnancy;
• pregnancy with a risk of sex-linked genetic disorders;
• planning further pregnancy management;
• inconclusive fetal sex assessment by ultrasound;
• determination of fetal sex for medical indications.

Testing Method

The test is performed using molecular genetic analysis of cell-free fetal DNA (cfDNA) isolated from the pregnant woman's venous blood.

Procedure

• a venous blood sample is collected from the pregnant woman;
• blood collection is performed using the standard venipuncture procedure;
• cell-free fetal DNA is isolated from the blood sample;
• the sample is analyzed for the presence of Y chromosome-specific DNA sequences;
• blood collection takes only a few minutes and does not require hospitalization.

Sources:

https://www.sciencedaily.com/releases/2018/12/181215141333.htm
https://www.ncbi.nlm.nih.gov/books/NBK222286/
https://embryo.asu.edu/pages/sex-determination-humans
https://www.news-medical.net/health/How-is-the-Sex-of-a-Fetus-Determined.aspx
https://www.ncbi.nlm.nih.gov/books/NBK557601/

IMPORTANT!

It is crucial to remember that the information provided in this section is not intended for self-diagnosis or self-treatment. If you experience any pain or exacerbation of a condition, it is essential to consult a healthcare professional for proper diagnosis and treatment. Only a qualified specialist can provide an accurate diagnosis and recommend appropriate treatment. To obtain the most accurate and consistent evaluation of test results, it is recommended to perform them in the same laboratory. This is because different laboratories may use various methods and units of measurement for similar tests.