Human chorionic gonadotrophin, hCG
We remind you that independent interpretation of the results is unacceptable, the information provided below is for reference purposes only.
Total chorionic gonadotropin (hCG) is a hormone produced primarily by the trophoblastic cells of the placenta following embryo implantation. Measuring total hCG (hCG + Beta) in the blood allows for the early detection and monitoring of pregnancy.
The concentration of this hormone rises rapidly during the first weeks of pregnancy, and changes in its levels can provide important information about pregnancy development. In certain clinical situations, hCG testing is also used to evaluate conditions associated with abnormal secretion of this hormone.
Indications
- Early confirmation of pregnancy.
- Monitoring pregnancy progression during the first weeks.
- Evaluation of suspected ectopic pregnancy.
- Investigation of suspected nonviable pregnancy or miscarriage.
- Monitoring after pregnancy termination or spontaneous miscarriage.
- Diagnosis and monitoring of gestational trophoblastic disease.
- Evaluation and monitoring of certain hCG-secreting tumors, as recommended by a physician.
Procedure
The test is performed using a venous blood sample collected by qualified healthcare personnel. The concentration of hCG is measured using laboratory immunoassay methods.
Depending on the clinical indication, the test may be repeated after approximately 48 hours to assess changes in hormone levels over time.
Interpretation of Results
hCG levels are interpreted based on the clinical context, estimated gestational age, and the laboratory's reference ranges.
During early pregnancy, evaluating changes in hCG concentration over time may be more informative than a single measurement.
A single hCG result is not sufficient to determine the viability or location of a pregnancy. Results should be interpreted by a physician in conjunction with the patient's symptoms, medical history, and, when necessary, ultrasound findings.
Sources:
https://americanpregnancy.org/getting-pregnant/hcg-levels/
http://en.wikipedia.org/wiki/Human_chorionic_gonadotropin
https://www.healthline.com/health/mens-health/hcg
https://www.medicalnewstoday.com/articles/hcg-levels
https://www.babycenter.com/pregnancy/health-and-safety/hcg-levels_40007974
https://www.clearblue.com/pregnancy-tests/hcg
https://my.clevelandclinic.org/health/articles/22489-human-chorionic-gonadotropin
IMPORTANT!
It is crucial to remember that the information provided in this section is not intended for self-diagnosis or self-treatment. If you experience any symptoms or a worsening of a condition, it is essential to consult a healthcare professional for proper diagnosis and treatment. Only a qualified specialist can make an accurate diagnosis and determine the appropriate treatment. For the most accurate and consistent evaluation of test results, it is recommended to have them performed at the same laboratory. This is because different laboratories may use different methods and units of measurement for similar tests.
Preparation:
- Blood collection must be performed on an empty stomach or at least 3–4 hours after the last meal, according to laboratory requirements.
- Drinking still water before blood collection is permitted.
- Avoid intense physical activity before sample collection.
- Inform healthcare personnel about any medications or hormonal treatments you are taking, particularly those containing hCG.
- When monitoring pregnancy progression, follow the testing intervals recommended by your physician.