HOMA Index - Insulin Resistance
The HOMA index (Homeostatic Model Assessment) is a calculated laboratory parameter used to assess insulin resistance and the functional state of carbohydrate metabolism. It helps determine how effectively the body’s cells respond to insulin and how well the pancreas is functioning in terms of insulin secretion.
Indications
- suspected insulin resistance
- metabolic syndrome
- overweight or obesity
- carbohydrate metabolism disorders
- elevated blood glucose levels
- elevated insulin levels
- risk of type 2 diabetes mellitus
- comprehensive assessment of endocrine and metabolic status
Procedure
The HOMA index is calculated based on a venous blood sample. Using fasting glucose and insulin values, the laboratory automatically computes the HOMA-IR index using a specific formula. No additional intervention is required from the patient, as this is a fully calculated laboratory parameter.
Sources:
https://diabetesjournals.org/care/article/27/6/1487/22836/Use-and-Abuse-of-HOMA-Modeling
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287763/
https://labs.selfdecode.com/blog/homa-ir/
https://en.wikipedia.org/wiki/Homeostatic_model_assessment
https://www.sciencedirect.com/topics/medicine-and-dentistry/homeostatic-model-assessment
IMPORTANT!
It is crucial to remember that the information provided in this section is not intended for self-diagnosis or self-treatment. If you experience any pain or exacerbation of a condition, it is essential to consult a doctor for diagnostic tests and proper treatment. Only a qualified specialist can make an accurate diagnosis and determine the appropriate treatment. To obtain the most accurate and consistent evaluation of test results, it is recommended to have them conducted in the same laboratory. This is because different laboratories may use varying methods and units of measurement for similar tests.
Preparation:
- the test must be performed strictly fasting (8–12 hours without food)
- only plain water is allowed in the morning before sampling
- 24 hours before the test it is recommended to avoid overeating, avoid alcohol consumption, and avoid intense physical activity
- after medical consultation, temporary discontinuation of medications affecting glucose and insulin levels may be required