Liver Profile
Liver function profile is a laboratory panel used to assess the functional state of the liver, biliary system, and protein metabolism. It helps detect liver cell damage, inflammatory processes, bile flow disturbances, and evaluate the liver’s synthetic function.
Indications
- suspected liver or biliary tract diseases
- jaundice (skin or scleral yellowing)
- pain or discomfort in the right upper abdomen
- bitter taste in the mouth, digestive disturbances
- monitoring of chronic liver diseases (hepatitis, steatosis, etc.)
- long-term use of hepatotoxic medications
- preventive health screening
Composition
- Alanine aminotransferase (ALT)
- Aspartate aminotransferase (AST)
- Total bilirubin
- Direct bilirubin
- Gamma-glutamyl transferase (GGT)
- Alkaline phosphatase (ALP)
- Total protein
- Cholinesterase
Contraindications
There are no absolute contraindications. The test may be temporarily postponed in case of:
- acute infectious diseases
- severe acute conditions (as determined by a physician)
Procedure
The test is performed on an outpatient basis and involves venous blood sampling. No special instrumental procedures are required. After testing, results are provided with medical interpretation.
Sources:
https://www.healthline.com/health/liver-function-tests
https://medlineplus.gov/lab-tests/liver-function-tests/
https://en.wikipedia.org/wiki/Liver_function_tests
https://my.clevelandclinic.org/health/diagnostics/17662-liver-function-tests
https://www.mayoclinic.org/tests-procedures/liver-function-tests/about/pac-20394595
https://www.ncbi.nlm.nih.gov/books/NBK482489/
https://www.merckmanuals.com/-/media/Manual/LabTests/LiverFunctionTests.html
https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/common-liver-tests
IMPORTANT!
It is crucial to remember that the information provided in this section is not intended for self-diagnosis or self-treatment. If you experience pain or a worsening of symptoms, it is essential to consult a qualified healthcare professional for proper diagnosis and treatment. Only a licensed medical practitioner can accurately diagnose and prescribe appropriate treatment. To ensure the most accurate and consistent evaluation of test results, it is recommended to have the tests performed at the same laboratory. Different laboratories may use varying methods and units of measurement for similar tests.
Preparation:
- blood sampling in the morning on an empty stomach (8–12 hours fasting)
- avoid alcohol and fatty foods for 24 hours before testing
- do not smoke 1–2 hours before the procedure
- avoid intense physical activity prior to testing
- a small amount of still water is allowed