Rheumatology Profile - extended
Extended rheumatic tests are a comprehensive laboratory panel used for the detection of autoimmune, systemic, and inflammatory connective tissue diseases, as well as for a more detailed assessment of the body’s immunological activity. The panel allows for the early detection of a wide range of autoimmune processes, including systemic involvement of organs and tissues.
Indications
- suspected systemic autoimmune diseases
- prolonged joint and muscle pain with inflammation
- chronic fatigue and unexplained weakness
- unexplained elevation of inflammatory markers
- suspicion of systemic lupus erythematosus and other connective tissue diseases
- recurrent or persistent inflammatory conditions
- monitoring of known autoimmune diseases
Composition
- C-reactive protein (CRP)
- Anti-streptolysin O (ASL-O)
- Rheumatoid factor (RF, IgM)
- Autoimmune antibody screening: ANA, AMA, LKM, ASMA
Contraindications
There are no absolute contraindications. The test may be temporarily postponed in case of:
- acute infectious diseases
- severe exacerbation of chronic conditions (as determined by a physician)
Procedure
The test is performed on an outpatient basis and involves venous blood sampling. No special instrumental preparation is required. After testing, results are provided with medical interpretation.
Sources:
https://medlineplus.gov/lab-tests/ccp-antibody-test/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583789/
https://www.healthline.com/health/rheumatoid-arthritis-crp-levels
IMPORTANT!
It is crucial to remember that the information provided in this section is not intended for self-diagnosis or self-treatment. If you experience any pain or exacerbation of a condition, it is essential to consult a qualified medical professional for diagnostic tests and appropriate treatment. Only a qualified specialist can provide an accurate diagnosis and determine the appropriate course of treatment. To ensure the most accurate and consistent evaluation of test results, it is recommended to have them performed at the same laboratory. This is because different laboratories may use different methods and units of measurement for similar tests.
Preparation:
- blood sampling in the morning on an empty stomach (8–12 hours fasting)
- avoid alcohol and intense physical activity for 24 hours before testing
- do not smoke 1–2 hours before the procedure
- a small amount of still water is allowed
- avoid stress when possible before testing