Testosterone total
Total testosterone is the main androgen hormone in the human body, produced primarily in the testes in men and in smaller amounts in the ovaries and adrenal cortex in women. It plays a key role in the development and maintenance of male sexual characteristics, reproductive function, muscle mass, bone density, and metabolic balance.
In circulation, testosterone exists in two forms: protein-bound (mainly to SHBG and albumin) and free, biologically active fraction. Measurement of total testosterone provides an overall assessment of androgen status and is widely used in the diagnosis of endocrine and reproductive disorders.
Indications
- Infertility evaluation
- Suspected male hypogonadism
- Assessment of delayed or precocious puberty
- Hirsutism, acne, or signs of hyperandrogenism in women
- Menstrual irregularities
- Decreased libido and sexual dysfunction
- Polycystic ovary syndrome (PCOS)
- Monitoring of hormonal or antiandrogen therapy
- Assessment of endocrine disorders in metabolic diseases
Procedure
Total testosterone is measured from a venous blood sample, usually taken from a vein in the antecubital fossa. The procedure is quick, minimally invasive, and well tolerated. After blood collection, mild discomfort or a small bruise may occur. The sample is then analyzed in the laboratory to determine hormone concentration.
Sources:
https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=testosterone_total
https://my.clevelandclinic.org/health/diagnostics/24215-testosterone-test
https://www.verywellhealth.com/testosterone-levels-5212199
https://www.webmd.com/a-to-z-guides/testosterone-test
https://honehealth.com/edge/health/testosterone-levels-by-age/
https://www.medicalnewstoday.com/articles/323085
IMPORTANT!
It is crucial to remember that the information provided here is not intended for self-diagnosis or self-treatment. If you experience any symptoms or exacerbation of a condition, it is essential to consult a qualified healthcare professional for proper diagnosis and treatment. Only a qualified specialist can accurately diagnose and recommend appropriate treatment. To ensure the most accurate and consistent evaluation of test results, it is recommended to have tests performed at the same laboratory. Different laboratories may use varying methods and units of measurement for similar tests.
Preparation:
- Blood collection is recommended in the morning, between 07: 30 and 11: 00
- The test should be performed in a fasting state (8–12 hours fasting), water is allowed
- Avoid alcohol, intense physical activity, and significant stress for 24 hours before testing
- Do not smoke for 1–3 hours before the test
- Inform medical staff about any medications taken (hormones, oral contraceptives, steroids/anabolic agents, thyroid hormones, biotin/vitamin B7, etc. )
- Treatment should not be stopped without medical advice
- In women, the day of the menstrual cycle should be noted; for hyperandrogenism evaluation, sampling is preferably done on days 2–4 of the cycle unless otherwise indicated
- Pregnancy status, menopause, and use of hormonal therapy or contraception should be reported
- In men, low values should be interpreted in clinical context and may require confirmation with a repeat morning sample