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Men's Health After 40: Prostate Under Protection

  • 12 February 2026
  • eye 6
Men's Health After 40: Prostate Under Protection
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As men age, their bodies gradually change, adapting to new conditions. Hormones, metabolism, and the reproductive system undergo subtle changes. Often, men do not notice the first “warning” signs. But there is a key and most vulnerable area that requires attention after 40 years — the prostate.

The prostate is a small gland located below the bladder and surrounding the urethra, which plays a key role in maintaining the health of the male urinary system by controlling the flow of urine and helping prevent congestion in the pelvic area. The functional state of the prostate can be monitored using the prostate-specific antigen (PSA) test, which reflects possible changes in the gland and helps detect abnormalities in a timely manner.

PSA: the secret signal of your body

PSA (Prostate-Specific Antigen) is a protein produced by prostate cells. It helps liquefy semen and supports normal reproductive function.

Important: Elevated PSA levels do not automatically mean a diagnosis of “cancer.” It is a marker indicating possible changes in the prostate and requiring further examination and attention.

Fact: The risk of developing prostate cancer before 40–45 years is very low, but after 45–50 years it begins to increase significantly, rising sharply between 60 and 85 years. This type of cancer is considered one of the most aggressive in men.

Situations where PSA may be elevated:

  • Prostate inflammation (prostatitis)
  • Benign prostatic hyperplasia
  • Structural tissue changes
  • Abnormal cell growth

PSA screening is supported by leading global organizations:

  • WHO emphasizes the importance of regular monitoring of men’s health after 40 and early detection of urological diseases for timely intervention.

  • American Urological Association (AUA) recommends discussing the PSA test with a doctor starting at age 45 for men with average risk, and from age 40 for men with increased risk (African Americans, family history of prostate cancer).

  • European Association of Urology (EAU) also stresses that PSA screening is a key tool for early detection of prostate problems and reduces the risk of late diagnosis.

Expert advice: discuss your PSA test with your urologist and establish an individualized monitoring plan.

At Invitro Diagnostics, the total Prostate-Specific Antigen (tPSA) test is performed using modern, high-precision methods. Venous blood is drawn from the elbow vein, placed in special tubes with anticoagulant, and transported to the laboratory for analysis. The procedure takes only a few minutes.

Plus: fast, painless, and accurate results.

More detailed information can be found here.

Sources:

[1] https://www.who.int/ru/news-room/feature-stories/detail/men%E2%80%99s-health-checklist

[2] https://www.auanet.org/guidelines-and-quality/guidelines/early-detection-of-prostate-cancer-guidelines

[3] https://pubmed.ncbi.nlm.nih.gov/23856038/

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