Aspergillus fumigatus, M3

Aspergillus fumigatus is a type of fungus that can cause respiratory infections or allergic reactions, especially in people with weakened immunity or chronic lung conditions. The test detects the presence of specific antibodies or antigens of Aspergillus fumigatus in blood or other biological samples.

Role

• Diagnosis of aspergillosis (invasive or superficial)
• Assessment of immune sensitivity to Aspergillus fumigatus (allergic reactions, asthma, allergic bronchopulmonary aspergillosis)
• Guiding antifungal treatment or preventive measures

Indications

• Suspected pulmonary or systemic aspergillosis
• Patients with persistent respiratory symptoms, fever, cough, or hemoptysis
• Immunodeficiencies (transplant, chemotherapy, HIV)
• Monitoring antifungal therapy

Procedure

• The test is performed on a blood sample (serum or plasma)
• Laboratory methods include ELISA, PCR, or immunochromatography to detect specific antigens or antibodies

Advantages

• Non-invasive, fast, and safe
• Helps in early detection of fungal infections
• Allows monitoring of treatment and disease progression

Interpretation of results

• Positive result: suggests the presence of an infection or immune response to Aspergillus fumigatus; further clinical evaluation is required
• Negative result: no antibodies/antigens detected; active infection risk is low but not completely excluded